One of my old blogs has been turned into a full article on the Adobe Developer Connection and updated for Flex 3 Beta 2 & Adobe AIR Beta 2:
Building an Adobe AIR application on salesforce.com with Flex 3
Also a recording of the session that I hosted at Dreamforce has been posted on the Apex Developer Network:
Make Your App *Bling*: Build Amazing Salesforce Apps Using Adobe Tech. (click on “Apex & Beyond” then scroll down to the session)
Lastly, in the next few weeks we will be releasing an update to the Flex Toolkit for Apex which adds simple local caching for AIR applications. More information as soon as we finishing implementing the basic CRUD functions.